Drug antagonism.
نویسندگان
چکیده
منابع مشابه
An R Package for Assessing Drug Synergism/Antagonism
This introduction to the R package mixlow is a (slightly) modified version of Boik and Narasimhan (2010), published in the Journal of Statistical Software. Synergistic and antagonistic drug interactions are important to consider when developing mixtures of anticancer or other types of drugs. Boik, Newman, and Boik (2008) proposed the MixLow method as an alternative to the Median-Effect method o...
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CC-BY 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract 1 Although drug combinations have proven efficacious in a variety of diseases, the design of such 2 regimens often involves extensive experimental screening due to the myriad choice of drugs and 3 doses. To address these challenges, we...
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The median-effect equation derived from the mass-action law principle at equilibrium-steady state via mathematical induction and deduction for different reaction sequences and mechanisms and different types of inhibition has been shown to be the unified theory for the Michaelis-Menten equation, Hill equation, Henderson-Hasselbalch equation, and Scatchard equation. It is shown that dose and effe...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5762.651